Primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection
Primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection
Definition
Primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection is a rare primary immunodeficiency due to a defect in innate immunity disorder characterized by selective susceptibility to viral infections, particularly after systemic challenge with live viral vaccines, such as the measles, mumps and rubella (MMR) vaccine. Patients present severe, potentially fatal, manifestations to viral illness, including encephalitis, hepatitis and pneumonitis.
Also known as IMD44, immunodeficiency 44, immunodeficiency type 44, primary immunodeficiency with post-MMR vaccine viral infection — per MONDO