Alpha-heavy chain disease

Alpha-heavy chain disease

Definition

Alpha-heavy chain disease (alpha-HCD) is a type of HCD characterized by the production of incomplete monoclonal alpha-heavy chains without associated light chains. Alpha-HCD is considered to be a subtype of immunoproliferative small intestinal disease (IPSID). The clinical presentation includes chronic diarrhea with evidence of malabsorption.

Also known as alpha chain disease, Alpha heavy chain disease, Alpha-HCD, Immunoproliferative small intestinal disease, IPSID, Mediterranean abdominal lymphoma, Mediterranean lymphoma, Mediterraneanl lymphoma — per MONDO

Also identified as

Affected Organs

Organ Involvement Source
Alimentary part of gastrointestinal system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Alimentary part of gastrointestinal system Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Intestine Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Intestine Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Lymphoid system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Lymphoid system Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Small intestine Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Small intestine Disease Has Primary Anatomic Site NCIT · CC BY 4.0