Diffuse lymphatic malformation
Diffuse lymphatic malformation
Definition
A rare developmental defect during embryogenesis characterized by multifocal dilated lymphatic vessels involving multiple organs and tissues. Patients mostly present in infancy and childhood. Clinical course and prognosis depend on the affected sites and extent of the condition, deterioration of lung function being a major cause of morbidity and mortality.
Also known as diffuse lymphangioma, diffuse lymphangiomatosis, disseminated lymphangioma, disseminated lymphangiomatosis, disseminated lymphatic malformation, generalised lymphatic anomaly, generalized lymphatic anomaly, GLA — per MONDO