Multiple carboxylase deficiency
ICD-10 Code
D81.81
Multiple carboxylase deficiency
Definition
Multiple carboxylase deficiency (MCD) is a term used to describe inborn errors of biotin metabolism characterized by reduced activities of biotin-dependent enzymes resulting in a wide spectrum of symptoms, including feeding difficulty, breathing difficulties, lethargy, seizures, skin rash, alopecia, and developmental delay.
Also known as MCD, multiple carboxylase deficiency — per MONDO