Hyperplastic polyposis syndrome
Hyperplastic polyposis syndrome
Definition
Hyperplastic polyposis syndrome is a rare, genetic intestinal disease characterized by the presence of multiple (usually large) hyperplastic/serrated colorectal polyps, usually with a pancolonic distribution. Histology reveals hyperplastic polyps, sessile serrated adenomas (most common), traditional serrated adenomas or mixed polyps. It is associated with an increased personal and familial (first-degree relatives) risk of colorectal cancer.
Also known as serrated polyposis — per MONDO
Also identified as
Affected Organs
| Organ | Involvement | Source |
|---|---|---|
| Alimentary part of gastrointestinal system | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Digestive tract | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Intestine | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Large intestine | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Lower digestive tract | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |