Macrophage activation syndrome
Macrophage activation syndrome
Definition
A complication of rheumatic disease that is caused by excessive activation and uncontrolled proliferation of T lymphocytes and well-differentiated macrophages. It is characterized by fever, pancytopenia, liver insufficiency, coagulopathy and neurologic symptoms.
Also known as MAS, reactive hemophagocytic lymphohistiocytosis — per MONDO