Castleman disease

ICD-10 Code D47.Z2

Castleman disease

Definition

Castleman disease (CD) is a benign lymphoproliferative disorder that may present as a localized or multicentric form. The clinical manifestations are heterogeneous, ranging from asymptomatic discrete lymphadenopathy to recurrent episodes of diffuse lymphadenopathy with severe systemic symptoms.

Also known as AFLH, angiofollicular ganglionic hyperplasia, angiofollicular lymph hyperplasia, angiofollicular lymph node hyperplasia, angiofollicular lymphoid hyperplasia, Castleman disease, Castleman's disease, Castleman's tumor, Castleman's tumour, giant lymph node hyperplasia, GLNH — per MONDO

Also identified as

Affected Organs

Organ Involvement Source
Lymphoid system Disease Has Primary Anatomic Site NCIT · CC BY 4.0

Drugs indicated

Drug Relation Source
Siltuximab may treat MEDRT · Public domain (U.S. Government work)