Palmoplantar pustulosis

Definition

A rare skin disease characterized by chronic eruption of sterile pustules on an erythematous and desquamative background, affecting the palms and soles, sometimes also the lateral aspects of hands and feet. The lesions are usually painful. Nail lesions (such as nail pitting, onycholysis, subungual pustules, and nail dystrophy) are also observed. The condition takes a chronic and relapsing course. Typical associations are psoriatic arthritis, thyroid gland dysfunction, and smoking.

Also known as localised pustular psoriasis, localized pustular psoriasis, LPP, Palmoplantar Pustulosis, PPP, pustulosis of palm and sole, pustulosis palmaris et plantaris — per MONDO

Also identified as

• DOID 4398 per MONDO
• ICD10CM L40.3 per MONDO
• ICD9 696.1 per MONDO
• NCIT C34888 per MONDO
• Orphanet 163927 per MONDO
• SCTID 27520001 per MONDO
• SCTID 81271001 per MONDO
• UMLS C0030246 per MONDO

Affected Organs