Diazoxide-resistant diffuse hyperinsulinism
Diazoxide-resistant diffuse hyperinsulinism
Definition
Diazoxide-resistant diffuse hyperinsulism (DRDH) is a form of Diazoxide resistant hyperinsulinism characterized by recurrent episodes of profound hypoglycemia caused by an excessive/ uncontrolled insulin secretion (inappropriate for the level of glycemia) due to diffuse involvement of pancreas that is unresponsive to medical treatment with diazoxide, often necessitating near total/total pancreatectomy.
Also known as hyperinsulinemic hypoglycemia, diazoxide-resistant diffuse form — per MONDO