Aminopterin/methotrexate embryofetopathy
Aminopterin/methotrexate embryofetopathy
Definition
Aminopterin/Methotrexate embryofetopathy is a syndrome of developmental anomalies characterized by growth deficiency, facial dysmorphism and skull, limb and neural defects secondary to maternal exposure to aminopterin or methotrexate (MTX) during pregnancy.
Also known as aminopterin embryopathy syndrome, fetal aminopterin syndrome, foetal aminopterin syndrome — per MONDO