Immune-mediated necrotizing myopathy
Immune-mediated necrotizing myopathy
Definition
Necrotizing autoimmune myopathy (NAM) is a rare form of idiopathic inflammatory myopathy characterized clinically by acute or subacute proximal muscle weakness, and histopathologically by myocyte necrosis and regeneration without significant inflammation.
Also known as anti-HMG-CoA myopathy, anti-SRP myopathy, autoimmune necrotizing myositis, immune myopathy with myocyte necrosis, IMNM, NAM — per MONDO