Atypical hemolytic-uremic syndrome
Atypical hemolytic-uremic syndrome
Definition
A rare, genetic thrombotic microangiopathy due to dysregulation of the alternative complement pathway and characterized by the triad of hemolytic anemia, thrombocytopenia, and acute renal dysfunction.
Also known as aHUS, Atypical Hemolytic Uremic Syndrome, atypical HUS, D-HUS, hemolytic-uremic syndrome without diarrhea, hemolytic-uremic syndrome without diarrhoea, non-diarrhea-associated hemolytic uremic syndrome — per MONDO
Also identified as
- DOID 0080301 per MONDO
- MESH D065766 per MONDO
- NCIT C123223 per MONDO
- Orphanet 2134 per MONDO
- UMLS C2931788 per MONDO
Drugs indicated
| Drug | Relation | Source |
|---|---|---|
| Eculizumab | may treat | MEDRT · Public domain (U.S. Government work) |
| Ravulizumab | may treat | MEDRT · Public domain (U.S. Government work) |