High-grade neuroendocrine carcinoma of the cervix uteri
High-grade neuroendocrine carcinoma of the cervix uteri
Definition
High-grade neuroendocrine carcinoma of the cervix uteri is a rare, aggressive, primary cervical neoplasm, originating from neuroendocrine cells present in the lining epithelium of the cervix, characterized, macroscopically, by usually large lesions, sometimes with a barrel-shaped appearance. Patients often present with abnormal vaginal bleeding or discharge, pelvic/abdominal pain, post-coital spotting and/or dysuria, while symptoms related to carcinoid syndrome are not frequent.
Also known as high-grade neuroendocrine carcinoma of the uterine cervix, poorly differentiated neuroendocrine carcinoma of the cervix uteri, poorly differentiated neuroendocrine cervical carcinoma — per MONDO
Also identified as
Affected Organs
| Organ | Involvement | Source |
|---|---|---|
| Cervix | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Cervix | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Endocrine gland | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Endocrine gland | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Female reproductive system | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Female reproductive system | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Genitourinary system | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Genitourinary system | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Reproductive system | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Uterus | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |