Primitive neuroectodermal tumor of the cervix uteri
Primitive neuroectodermal tumor of the cervix uteri
Definition
Primitive neuroectodermal tumor of the cervix uteri is a rare cancer of cervix uteri derived from neural crest cells, histologically composed of small, round neoplatic cells with variable degree of neural, glial and ependymal differentiation. Macroscopically, the tumor is often a large, soft, poorly circumscribed mass with infiltrative borders and necrotic areas. It presents with dysfunctional vaginal bleeding or discharge, lower abdominal pain and uterine enlargement.
Also known as cervical malignant peripheral neuroectodermal tumor, cervical malignant peripheral neuroectodermal tumour, cervical peripheral neuroectodermal cancer, malignant peripheral neuroectodermal tumor of the cervix uteri, malignant peripheral neuroectodermal tumour of the cervix uteri, peripheral neuroectodermal cancer of cervix uteri — per MONDO