Attenuated familial adenomatous polyposis

Definition

Attenuated familial adenomatous polyposis (AFAP) is a mild form of familial adenomatous polyposis characterized by the presence of fewer than 100 adenomatous colonic polyps, a more proximal colonic location, a delayed age of colorectal cancer (CRC) onset and a more limited expression of the extracolonic features.

Also known as AAPC, AFAP, attenuated adenomatous polyposis coli, attenuated familial adenomatous polyposis, attenuated familial polyposis coli, attenuated FAP, hereditary flat adenoma syndrome, HFAS — per MONDO

Also identified as

• MESH C538265 per MONDO
• NCIT C6729 per MONDO
• Orphanet 220460 per MONDO
• SCTID 715866009 per MONDO
• UMLS C2674616 per MONDO

Affected Organs