Yolk sac tumor of central nervous system

Yolk sac tumor of central nervous system

Definition

A malignant germ cell tumor of the central nervous system composed of primitive-appearing epithelial cells - putatively representing yolk sac endoderm - set in a loose, variably cellular, and often conspicuously myxoid matrix, resembling extra-embryonic mesoblast. Eosinophilic hyaline globules immunoreactive for AFP are a diagnostic feature. (WHO)

Also known as central nervous system yolk Sac tumor, central nervous system yolk Sac tumour, CNS yolk Sac tumor, CNS yolk Sac tumour, endodermal sinus tumor of central nervous system, endodermal sinus tumor of CNS, endodermal sinus tumour of central nervous system, endodermal sinus tumour of CNS, intracranial endodermal sinus tumor, intracranial endodermal sinus tumour, intracranial yolk sac tumor, intracranial yolk sac tumour, yolk Sac tumor of central nervous system, yolk Sac tumor of CNS, yolk Sac tumor of the central nervous system, yolk Sac tumor of the CNS, yolk Sac tumour of central nervous system, yolk Sac tumour of CNS, yolk Sac tumour of the central nervous system, yolk Sac tumour of the CNS — per MONDO

Also identified as

Affected Organs

Organ Involvement Source
Central nervous system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Central nervous system Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Nervous system Disease Has Associated Anatomic Site NCIT · CC BY 4.0