Adult-onset non-insulinoma persistent hyperinsulinemic hypoglycemia
Adult-onset non-insulinoma persistent hyperinsulinemic hypoglycemia
Definition
Diazoxide-resistant hyperinsulism (DRH) is form of congenital isolated hyperinsulinism caused by an abnormal insulin production by b-cells in the pancreas that can be diffuse or focal and is characterized by an excessive/ uncontrolled insulin secretion (inappropriate for the level of glycemia), recurrent episodes of profound hypoglycemia and resistance to medical management with diazoxide
Also known as NI-PHH — per MONDO