Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly

Definition

A rare form of diffuse large B-cell lymphoma occurring most commonly in patients over the age of 50 (usually between 70-75 years of age), without overt immunodeficiency, and presenting with nodal and extranodal involvement (in sites such as the stomach, lung, skin and pancreas) and B symptoms (fever, night sweats, weight loss). The tumor is characterized by an aggressive course and a short survival rate.

Also known as age-related EBV Positive B-cell lymphoproliferative disorder, EBV Positive diffuse large B-cell lymphoma of the elderly, EBV-Positive diffuse large B-cell lymphoma, NOS, EBV-positive DLBCL of the elderly, Epstein-Barr Virus Positive diffuse large B-cell lymphoma of the elderly, Senile EBV-associated B-cell lymphoproliferative disorder — per MONDO

Also identified as

• NCIT C80281 per MONDO
• Orphanet 289661 per MONDO
• SCTID 716788007 per MONDO
• UMLS C2700007 per MONDO

Affected Organs