Splenic diffuse red pulp small B-cell lymphoma
Splenic diffuse red pulp small B-cell lymphoma
Definition
Splenic diffuse red pulp small B-cell lymphoma is a rare, indolent B-cell non-Hodgkin lymphoma characterized by abnormal proliferation of small, monomorphous, basophilic B-lymphocytes, with villous cytoplasm, in the splenic red pulp, bone marrow and peripheral blood. It typically presents in the late clinical stages with splenomegaly and moderate lymphocytosis. Cytopenias are rare and likely associated with hypersplenism.
Also known as SDRPL, splenic diffuse red pulp lymphoma — per MONDO
Also identified as
Affected Organs
| Organ | Involvement | Source |
|---|---|---|
| Lymphoid system | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Spleen | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Spleen | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |