Hairy cell leukemia variant

Hairy cell leukemia variant

Definition

Hairy Cell Leukemia variant (HCL-V) is defined as a rare and indolent form of small, mature, B-cell leukemia characterized by splenomegaly, an elevated white blood cell (WBC) count and hyper-cellular bone marrow. HCL-V is more aggressive and resistant to therapy than classical HCL (HCL-C).

Also known as hairy cell leukemia variant, HCL-V, leukemic reticuloendotheliosis variant, prolymphocytic variant of hairy cell leukaemia, prolymphocytic variant of hairy cell leukemia, prolymphocytic variant of HCL — per MONDO

Also identified as

Affected Organs

Organ Involvement Source
Bone marrow Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Lymphoid system Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Spleen Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Spleen Disease Has Primary Anatomic Site NCIT · CC BY 4.0