Gastric adenocarcinoma and proximal polyposis of the stomach

Gastric adenocarcinoma and proximal polyposis of the stomach

Definition

An autosomal dominant disorder caused by specific pathogenic variants in the APC gene promoter, characterized by proximal gastric polyposis and an increased risk of gastric adenocarcinoma.

Also known as APC-related gastric adenocarcinoma and proximal polyposis of the stomach, familial fundic gland polyposis with gastric cancer, fundic gland polyposis, GAPPS, polyposis of gastric fundus without polyposis coli, polyposis, gastric, polyposis, gastric, Dos Santos and de Magalhaes 1980 — per MONDO

Also identified as