Primary systemic amyloidosis
Primary systemic amyloidosis
Definition
Primary systemic amyloidosis (PSA) is a form of AL amyloidosis caused by the aggregation and deposition of insoluble amyloid fibrils derived from misfolded monoclonal immunoglobulin light chains usually produced by a plasma cell tumor and characterized by multiple organ involvement.
Also known as systemic AL amyloidosis, systemic amyloidosis, systemic Immunoglobulin Light chain amyloidosis — per MONDO
Also identified as
Affected Organs
| Organ | Involvement | Source |
|---|---|---|
| Lymphoid system | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |