Complement 3 glomerulopathy
Complement 3 glomerulopathy
Definition
A rare primary membranoproliferative glomerulonephritis characterized by complement dysregulation occurring in the fluid phase and in the glomerular microenvironment, which results in prominent complement C3 deposition in kidney biopsy samples.
Also known as C3 glomerulopathy, C3G, non-Ig-mediated membranoproliferative glomerulonephritis, non-Ig-mediated MPGN, non-immunoglobulin-mediated membranoproliferative glomerulonephritis, non-immunoglobulin-mediated MPGN — per MONDO