Acitretin/etretinate embryopathy
Acitretin/etretinate embryopathy
Definition
Acitretin/Etretinate embryopathy is a teratogenic disorder due to acitretin or etretinate exposure during the first trimester of pregnancy, carrying a risk of fetal malformations of approximately 20%, including central nervous system, craniofacial, ear, thymic, cardiac and limb anomalies.
Also known as fetal acitretin/etretinate syndrome, foetal acitretin/etretinate syndrome, retinoid embryopathy — per MONDO