Thrombotic thrombocytopenic purpura

Thrombotic thrombocytopenic purpura

Definition

Thrombotic thrombocytopenic purpura (TTP) is an aggressive and life-threatening form of thrombotic microangiopathy (TMA) characterized by profound peripheral thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and organ failure of variable severity and is comprised of congenital TTP and acquired TTP.

Also known as Moschcowitz disease, Moschowitz disease, TTP — per MONDO

Also identified as

Affected Organs

Organ Involvement Source
Blood vessel Disease Has Primary Anatomic Site NCIT · CC BY 4.0

Drugs indicated

Drug Relation Source
Caplacizumab may treat MEDRT · Public domain (U.S. Government work)