Cholangiocarcinoma

Cholangiocarcinoma

Definition

A carcinoma that arises from the intrahepatic biliary tree (intrahepatic cholangiocarcinoma) or from the junction, or adjacent to the junction, of the right and left hepatic ducts (hilar cholangiocarcinoma). Grossly, the malignant lesions are solid, nodular, and grayish. Morphologically, the vast majority of cases are adenocarcinomas. Signs and symptoms include malaise, weight loss, right upper quadrant abdominal pain, and night sweats. Early detection is difficult and the prognosis is generally poor.

Also known as CC, CCA, Cholangiocar.- intra/extrahepatic, cholangiocarcinoma, cholangiocarcinoma, intrahepatic and extrahepatic bile ducts (adenocarcinoma), cholangiocarcinoma, malignant, Cholangiocellular carcinoma — per MONDO

Also identified as

Affected Organs

Organ Involvement Source
Alimentary part of gastrointestinal system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Alimentary part of gastrointestinal system Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Bile ducts Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Bile ducts Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Biliary system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Biliary system Disease Has Primary Anatomic Site NCIT · CC BY 4.0

Drugs indicated

Drug Relation Source
Futibatinib may treat MEDRT · Public domain (U.S. Government work)
Pemigatinib may treat MEDRT · Public domain (U.S. Government work)