Loeffler endocarditis

Loeffler endocarditis

Definition

Loeffler's endocarditis is a rare restrictive cardiomyopathy characterized by hypereosinophilia and fibrous thickening of the endocardium, with usually large thrombi against the ventricle walls, that can lead to cardiovascular complications such as heart failure and thromboembolism. It manifests with symptoms like edema, fatigue and shortness of breath. It is usually secondary to eosinophil-associated tissue damage and is associated with idiopathic hypereosinophilic syndrome, chronic eosinophilic leukemia, carcinoma, or lymphoma.

Also known as eosinophilic endocarditis, eosinophilic endomyocardial disease — per MONDO

Also identified as

Affected Organs

Organ Involvement Source
Cardiovascular system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Cardiovascular system Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Heart Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Heart Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Respiratory system Disease Has Associated Anatomic Site NCIT · CC BY 4.0