Acquired generalized lipodystrophy
Acquired generalized lipodystrophy
Definition
Acquired generalized lipodystrophy belongs to a group of lipodystrophic syndromes characterized by loss of adipose tissue, and is a syndrome of insulin resistance that leads to increased cardiovascular risk. Acquired generalized lipodystrophy is related to a selective loss of subcutaneous adipose tissue occurring exclusively at the extremities (face, legs, arms, palms and sometimes soles).
Also known as acquired generalized lipodystrophy, acquired lipoatrophic diabetes, Lawrence syndrome, Lawrence-Seip syndrome — per MONDO