Antisynthetase syndrome
Antisynthetase syndrome
Definition
Antisynthetase (AS) syndrome is a clinically heterogeneous form of idiopathic inflammatory myopathy characterized by myositis, arthralgia, Raynaud phenomenon, mechanic hands, interstitial lung disease (ILD), and serum autoantibodies to aminoacyl transfer RNA synthetases (anti-ARS).
Also known as anti-Jo1 syndrome, AS syndrome — per MONDO