Nodal marginal zone B-cell lymphoma

Definition

Nodal marginal zone B-cell lymphoma is a rare, indolent B-cell non-Hodgkin lymphoma, characterized by abnormal clonal proliferation of mature B-lymphocytes with involvement of the lymph nodes, sometimes the bone marrow, and rarely the blood. Clinically it presents with disseminated peripheral, abdominal and/or thoracic lymphadenopathy. Cytopenia and bulky tumors (greater than 5 cm) are rare. Association with Hepatitis C virus and chronic inflammation has been reported.

Also known as Monocytoid B-cell lymphoma, NMZL, nodal marginal zone B-cell lymph., nodal marginal zone B-cell lymphoma, nodal marginal zone lymphoma — per MONDO

Also identified as

• DOID 0080211 per MONDO
• NCIT C8863 per MONDO
• Orphanet 86867 per MONDO
• SCTID 277623009 per MONDO
• UMLS C0855139 per MONDO

Affected Organs