Lymphomatoid granulomatosis

Definition

A very rare Epstein-Barr virus (EBV)-driven lymphoproliferative disease most commonly occurring in adults (in the fourth to sixth decade of life) and commonly affecting the lungs (with presentations varying from small bilateral pulmonary nodules to large necrotic and sometimes cavitating lesions), skin, central nervous system, and kidneys, but only very rarely affecting the lymph nodes and spleen. The symptoms associated with LYG depend on the site of disease involvement but mainly include cough, dyspnea or chest pain (in those with pulmonary involvement) and constitutional symptoms such as weight loss and fever.

Also known as LYG — per MONDO

Also identified as

• DOID 0081307 per MONDO
• MESH D008230 per MONDO
• NCIT C7930 per MONDO
• Orphanet 86869 per MONDO
• SCTID 239940004 per MONDO
• UMLS C0024307 per MONDO

Affected Organs