Aggressive NK-cell leukemia

Definition

A rare, highly aggressive, Epstein-Barr virus-associated leukemia, also known as aggressive NK-cell leukemia/lymphoma; it may represent the leukemic counterpart of nasal type extranodal NK/T-cell lymphomas. It affects primarily teenagers and young adults. It is characterized by the systemic proliferation of NK cells in the peripheral blood, bone marrow, liver, and spleen.

Also known as aggressive NK-cell leukaemia (morphologic abnormality), aggressive NK-cell leukemia, aggressive NK-cell leukemia (morphologic abnormality), aggressive NK-cell leukemia/lymphoma, aggressive NK-cell lymphoma, ANKCL, leukaemia (disease) of natural killer cell, leukemia (disease) of natural killer cell, natural killer cell leukaemia (disease), natural Killer cell leukemia, natural killer cell leukemia (disease), NK cell leukaemia, NK cell leukemia, NK-cell large granular lymphocyte leukaemia, NK-cell large granular lymphocyte leukemia, NK-cell leukaemia, NK-cell leukemia, NK-cell LGL leukaemia, NK-cell LGL leukemia — per MONDO

Also identified as

• DOID 1035 per MONDO
• NCIT C8647 per MONDO
• Orphanet 86873 per MONDO
• SCTID 721310007 per MONDO
• UMLS C1292777 per MONDO

Affected Organs