Anterior segment dysgenesis

Anterior segment dysgenesis

Definition

A spectrum of developmental anomalies that affect the development of the anterior segment of the eyeball resulting from abnormalities of neural crest migration and differentiation during embryologic development (Axenfeld-Rieger syndrome, Peters anomaly, posterior keratoconus, and iridoschisis).

Also known as anterior segment mesenchymal dysgenesis, anterior segment ocular dysgenesis, ASGD, ASMD, ASOD, familial ocular anterior segment mesenchymal dysgenesis — per MONDO

Also identified as