Hereditary von Willebrand disease
Hereditary von Willebrand disease
Definition
Hereditary von Willebrand disease (VWD) is a hereditary bleeding disorder caused by a genetic anomaly leading to quantitative, structural or functional abnormalities of the Willebrand factor (von Willebrand factor; VWF). Two major groups of VWF deficiency have been defined: quantitative and partial (type 1) or total (type 3), and qualitative (type 2) with several subtypes (2A, 2B, 2M, 2N).
Also known as congenital von willebrand's disease, hereditary von Willebrand disease, hereditary von Willebrand disease (hereditary or acquired) — per MONDO