Multicentric Castleman disease

Definition

Multicentric castleman disease (MCD) is an aggressive form of Castleman disease that mostly results from human herpesvirus 8 (HHV8) infection. It manifests by fever, diffuse lymphadenopathy, hepatosplenomegaly, Involvement of the respiratory system and increased C-reactive protein.

Also known as HHV-8-associated multicentric Castleman disease, Human herpesvirus-8-associated multicentric Castleman disease, MCD, multicentric Angiofollicular lymphoid hyperplasia, multicentric Castleman's disease — per MONDO

Also identified as

• DOID 0111152 per MONDO
• NCIT C27855 per MONDO
• Orphanet 570438 per MONDO
• Orphanet 93686 per MONDO
• UMLS C1334815 per MONDO

Affected Organs