Acute myeloid leukemia with 11q23 abnormalities

Definition

An acute myeloid leukemia associated with t(9;11)(p22.3;q23.3) and MLLT3-KMT2A fusion protein expression. Morphologically it usually has monocytic features. It may present at any age but it is more commonly seen in children. Patients may present with disseminated intravascular coagulation.

Also known as acute myeloid leukaemia with 11q23 (MLL) abnormalities, acute myeloid leukaemia with MLL abnormalities, acute myeloid Leukaemia with t(9;11)(p21.3;q23.3); MLLT3-KMT2A, acute myeloid leukaemia with t(9;11)(p22;q23); MLLT3-MLL, acute myeloid leukaemia with t(9;11)(p22.3;q23.3); MLLT3-KMT2A, acute myeloid leukemia with 11q23 (MLL) abnormalities, acute myeloid leukemia with MLL abnormalities, acute myeloid Leukemia with t(9;11)(p21.3;q23.3); MLLT3-KMT2A, acute myeloid leukemia with t(9;11)(p22;q23); MLLT3-MLL, acute myeloid leukemia with t(9;11)(p22.3;q23.3); MLLT3-KMT2A, AML with 11q23 abnormalities, AML with t(9;11)(p22;q23); MLLT3-MLL — per MONDO

Also identified as

• NCIT C82403 per MONDO
• Orphanet 98831 per MONDO
• SCTID 444911000 per MONDO
• UMLS C1292775 per MONDO

Affected Organs