Primary mediastinal large B-cell lymphoma
Primary mediastinal large B-cell lymphoma
Definition
A large B-cell non-Hodgkin lymphoma arising in the mediastinum. Morphologically it is characterized by a massive diffuse lymphocytic proliferation associated with compartmentalizing fibrosis. Response to intensive chemotherapy, with or without radiotherapy, is usually good. (WHO, 2001)
Also known as B-cell diffuse large cell lymphoma of mediastinum, B-cell diffuse large cell lymphoma of the mediastinum, large cell lymphoma of the mediastinum, Med-DLBCL, mediastinal (thymic) large B-cell lymphoma, mediastinal B-cell diffuse large cell lymphoma, mediastinal diffuse large cell lymphoma with sclerosis, mediastinal diffuse large-cell lymphoma with sclerosis, mediastinal large B-cell lymphoma, PMBL, PMLCL, primary mediastinal clear cell lymphoma of B-cell type, primary mediastinal large B-cell lymphoma — per MONDO
Also identified as
- DOID 0080210 per MONDO
- ICD10CM C85.2 per MONDO
- NCIT C9280 per MONDO
- Orphanet 98838 per MONDO
- SCTID 444910004 per MONDO
- UMLS C1292754 per MONDO
Affected Organs
| Organ | Involvement | Source |
|---|---|---|
| Lymphoid system | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Respiratory system | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Thymus | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Thymus | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |