Hand-Schuller-Christian disease
Hand-Schuller-Christian disease
Definition
A multifocal, unisystem form of Langerhans-cell histiocytosis. There is involvement of multiple sites in one organ system, most frequently the bone. Patients are usually young children presenting with multiple destructive bone lesions.
Also known as chronic multifocal Langerhans cell histiocytosis, classic multifocal Langerhans cell histiocytosis, hand-Schuller-Christian disease, multifocal eosinophilic granuloma, multifocal Unisystem Langerhans cell histiocytosis — per MONDO