Luminal A breast carcinoma
Luminal A breast carcinoma
Definition
A biologic subset of breast carcinoma defined by high expression of genes characteristic of luminal epithelial cells, including estrogen receptor (ER), estrogen regulated protein LIV-1, and the transcription factors hepatocyte nuclear factor 3, HNF3A, XBP1, and GATA 3. This subtype of breast cancer is associated with a good prognosis.
Also known as Luminal A, Luminal A breast cancer, Luminal A breast carcinoma, Luminal A estrogen receptor positive subtype of breast carcinoma, Luminal A oestrogen receptor positive subtype of breast carcinoma, Luminal A subtype of breast carcinoma — per MONDO
Also identified as
Affected Organs
| Organ | Involvement | Source |
|---|---|---|
| Breast | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Breast | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |