Ovarian granulosa cell tumor

Definition

A granulosa-stromal cell tumor that arises from the ovary. It is characterized by the presence of granulosa cells that comprise at least ten percent of the cellular population. The granulosa cells are often found in a background that contains theca and fibrous cells. There are two major subtypes recognized, adult and juvenile granulosa cell tumor. Clinically, patients may present with an abdominal mass. Symptoms depend on the patient's age. The most important indicator of prognosis is tumor stage. Age over forty years at the time of the initial diagnosis, large tumor size, bilaterality, cellular atypia, and increased mitotic activity are factors indicating a potentially aggressive clinical course and relative poor prognosis.

Also known as granulosa cell neoplasm of ovary, granulosa cell neoplasm of the ovary, granulosa cell tumor of ovary, granulosa cell tumor of the ovary, granulosa cell tumour of ovary, granulosa cell tumour of the ovary, ovarian granulosa cell neoplasm, ovarian granulosa cell tumor, ovary granulosa cell tumor, ovary granulosa cell tumour — per MONDO

Also identified as

• MESH C537296 per MONDO
• NCIT C6261 per MONDO
• SCTID 254863004 per MONDO
• UMLS C1370419 per MONDO

Affected Organs