Mediastinal yolk sac tumor

Definition

An extragonadal non-seminomatous malignant germ cell tumor that arises from the mediastinum. It is characterized by the presence of small pale cells with small amount of cytoplasm and round to oval nuclei with small nucleoli forming a variety of patterns, including microcystic, macrocystic, pseudopapillary, myxomatous, hepatoid, polyvesicular vitelline, and solid. It manifests with respiratory distress, thoracic pain, fever, and superior vena cava syndrome.

Also known as endodermal sinus neoplasm of mediastinum, endodermal sinus neoplasm of the mediastinum, endodermal sinus tumor of mediastinum, endodermal sinus tumor of the mediastinum, endodermal sinus tumour of mediastinum, endodermal sinus tumour of the mediastinum, mediastinal endodermal sinus neoplasm, mediastinal endodermal sinus tumor, mediastinal endodermal sinus tumour, mediastinal yolk Sac neoplasm, mediastinal yolk Sac tumor, mediastinal yolk Sac tumour, mediastinum yolk sac tumor, mediastinum yolk sac tumour, yolk Sac neoplasm of mediastinum, yolk Sac neoplasm of the mediastinum, yolk Sac tumor of mediastinum, yolk Sac tumor of the mediastinum, yolk Sac tumour of mediastinum, yolk Sac tumour of the mediastinum — per MONDO

Also identified as

• NCIT C6443 per MONDO
• UMLS C1334683 per MONDO

Affected Organs