Chronic mast cell leukemia

ICD-10 Code C94.3

Chronic mast cell leukemia

Definition

A rare form of mast cell leukemia characterized by the presence of at least 20% mast cells in bone marrow aspirate smears but often mature mast cell morphology, low proliferation rate, and absence of organ damage and C findings (cytopenias, hepatomegaly, ascites, portal hypertension, splenomegaly, skeletal lesions, malabsorption). The disease course is less aggressive than in the acute form, although patients may later progress.

Also known as Chronic MCL — per MONDO

Also identified as