Vulval Paget disease

Vulval Paget disease

Definition

An uncommon intraepithelial malignant neoplasm of eccrine or apocrine origin, arising from the vulva. It usually affects post-menopausal women. In approximately 10-20% of the cases there is an associated anorectal, or urothelial carcinoma or a skin appendage adenocarcinoma identified. It presents as a red, eczematous lesion. Microscopically, it is characterized by the presence of the typical Paget cells which are large, round cells with abundant cytoplasm and prominent nuclei.

Also known as mammalian vulva Paget disease, Paget disease of the vulva, Paget's disease of the vulva, Paget's disease of vulva, vulva Paget's disease, vulval Paget's disease, vulvar Paget's disease — per MONDO

Also identified as

Affected Organs

Organ Involvement Source
Exocrine system Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Female reproductive system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Female reproductive system Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Genitourinary system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Genitourinary system Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Integumental system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Reproductive system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Skin of body Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Skin of body Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Sweat glands Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Vulva Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Vulva Disease Has Primary Anatomic Site NCIT · CC BY 4.0