Familial adenomatous polyposis 4
Familial adenomatous polyposis 4
Definition
An autosomal recessive tumor predisposition syndrome characterized by the development of multiple colonic adenomas in adulthood, often with progression to colorectal cancer. Proliferative lesions in other tissues may also occur.
Also known as familial adenomatous polyposis 4, familial adenomatous polyposis type 4, FAP4, MSH3-related AFAP, MSH3-related attenuated familial adenomatous polyposis, MSH3-related attenuated familial polyposis coli, MSH3-related attenuated FAP — per MONDO