Myelofibrosis

Definition

A partial or complete replacement of the bone marrow stroma by fibrous tissue. It can be a primary bone marrow lesion as part of the chronic myeloproliferative disorders (chronic idiopathic myelofibrosis), a manifestation of acute myeloid leukemia (acute panmyelosis with myelofibrosis), or a secondary phenomenon due to bone marrow involvement by a metastatic tumor (e.g., metastatic breast carcinoma). --2003

Also known as myelofibrosis — per MONDO

Also identified as

• NCIT C3248 per MONDO
• UMLS C0026987 per MONDO

Affected Organs