Acute myeloid leukemia with mutated NPM1

Definition

An acute myeloid leukemia with mutation of the nucleophosmin gene. It is usually associated with normal karyotype and frequently has myelomonocytic or monocytic features. It usually responds to induction therapy.

Also known as acute myeloid leukaemia with cytoplasmic nucleophosmin, acute myeloid leukemia with cytoplasmic nucleophosmin, acute myeloid leukemia with mutated NPM1, acute myeloid leukemia, NPM1 gene mutation, AML with mutated NPM1, AML, Mutation of the Nucleophosmin Gene, AML, NPM1 gene mutation, AML, NPM1 Mutation, AML, Nucleophosmin Gene Mutation, NPMc+ AML — per MONDO

Also identified as

• DOID 0081089 per MONDO
• NCIT C82431 per MONDO
• UMLS C2826177 per MONDO

Affected Organs