Acute myeloid leukemia, KIT gene mutation

Definition

Any acute myeloid leukemia that has the chromosomal anomaly KIT gene mutation. (A molecular genetic abnormality that refers to mutation of the c-kit (CD117) proto-oncogene. It is associated with the development of gastrointestinal stromal tumor and gastrointestinal autonomic nerve tumor. It has also been described in acute myeloid leukemias, dysgerminomas, and seminomas.)

Also known as AML, c-KIT Gene Mutation, AML, C-KIT Mutation, AML, CD117 Gene Mutation, AML, CD117 Mutation, AML, KIT gene mutation, AML, KIT Proto-Oncogene Tyrosine Protein Kinase Gene Mutation, AML, V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog Gene Mutation — per MONDO