Cytokine release syndrome

ICD-10 Code D89.83

Cytokine release syndrome

Definition

A syndrome that occurs after therapeutic infusion of antibodies into the blood and is characterized by nausea, headache, tachycardia, hypotension, rash, and shortness of breath. It is caused by the release of cytokines from the cells that are targeted by the antibodies. Most patients experience a mild to moderate reaction; however, the reaction may be severe and life-threatening.

Also known as CRS, cytokine storm, cytokine-associated toxicity — per MONDO

Also identified as

Drugs indicated

Drug Relation Source
Tocilizumab may treat MEDRT · Public domain (U.S. Government work)