Dyskinesia with orofacial involvement, autosomal dominant
Dyskinesia with orofacial involvement, autosomal dominant
Definition
A rare paroxysmal movement disorder, with childhood or adolescent onset, characterized by paroxysmal choreiform, dystonic, and myoclonic movements involving the limbs (mostly distal upper limbs), neck and/or face, which can progressively increase in both frequency and severity until they become nearly constant. Patients may also present with delayed motor milestones, perioral and periorbital dyskinesias, dysarthria, hypotonia, and weakness.
Also known as dyskinesia, familial, with facial myokymia, FDFM — per MONDO