Acute myeloid leukemia, t(8;21)(q22; q22.1)

Acute myeloid leukemia, t(8;21)(q22; q22.1)

Definition

An acute myeloid leukemia associated with t(8;21)(q22;q22) resulting in RUNX1-RUNX1T1 fusion protein expression. The bone marrow and the peripheral blood show large myeloblasts with abundant basophilic cytoplasm, often containing azurophilic granules.

Also identified as